Periactin

Periactin

Generic name: Cyproheptadine hydrochloride
Brand names: Periactin

Why Periactin is prescribed

Periactin is an antihistamine given to help relieve cold- and allergy-related symptoms such as hay fever, nasal inflammation, stuffy nose, red and inflamed eyes, hives, and swelling. Periactin may also be given after epinephrine to help treat anaphylaxis, a life-threatening allergic reaction.

Some doctors prescribe Periactin to treat cluster headache and to stimulate appetite in underweight people.

The most important facts about Periactin

Like other antihistamines, Periactin may make you feel sleepy and sluggish. However, some people, particularly children, may have the opposite reaction and become excited.

How you should take Periactin

Take Periactin exactly as prescribed by your doctor.

If you miss a dose

If you have forgotten to take a dose, take it as soon as you recall. If it is almost time for the next dose, skip the missed one and get back to your regular schedule. Do not take two doses right away.

Storage instructions

Store Periactin at room temperature in a tightly closed container.

Side effects may be caused by Periactin

A drug cannot anticipate producing side effects. If any develop or change in intensity, tell your doctor immediately. Only your doctor can determine whether it is safe for you to continue taking Periactin.

• More common possible effects include:
  Anaphylaxis (life-threatening allergic reaction), anemia, appetite loss, chest congestion or tightness, chills, confusion, constipation, convulsions, diarrhea, difficulty urinating, dizziness, dry mouth, nose, or throat, earlier-than-expected menstrual period, exaggerated feeling of well-being, excessive perspiration, excitement, faintness, fatigue, fluttery or throbbing heartbeat, frequent urination, hallucinations, headache, hives, hysteria, inability to urinate, increased appetite and weight gain, insomnia, irritability, lack of coordination, light sensitivity, liver problems, low blood pressure, nausea, nervousness, rapid heartbeat, rash and swelling, restlessness, ringing in the ears, sleepiness, stomach pain, stuffy nose, tingling or pins and needles, tremor, vertigo, vision problems (double vision, blurred vision), vomiting, weight gain, wheezing, yellow eyes and skin

Older people, in particular, are likely to become dizzy or drowsy, or develop low blood pressure in response to Periactin.

When Periactin should not be prescribed

Do not take Periactin if you are sensitive to it, or have ever had an allergic reaction to it or to a similar antihistamine.

Do not take Periactin if you are taking an antidepressant drug known as an MAO inhibitor. Drugs in this category include Nardil and Parnate.

Do not take Periactin if you have the eye condition called angle-closure glaucoma, a peptic ulcer, an enlarged prostate, obstruction of the neck of the bladder, or obstruction of the outlet of the stomach.

Newborn or premature infants should not be given Periactin, nor should it be used by women who are breastfeeding an infant.

The elderly and those in a weakened condition should not take Periactin.

Special warnings about Periactin

Like other antihistamines, Periactin may make you drowsy or impair your coordination. Be very careful about driving, climbing, or operating machinery, or doing hazardous tasks until you know how you react to Periactin.

Be cautious about taking Periactin if you have bronchial asthma, the eye condition called glaucoma, an overactive thyroid gland, high blood pressure, heart disease, or circulatory problems.

Food and drugs that may interact with Periactin

Avoid alcoholic beverages while taking Periactin.

If you take Periactin with certain other drugs, the effects of either could be increased, decreased, or altered. It is extremely important to check with your doctor before combining Periactin with any of the following:

Antidepressant drugs classified as MAO inhibitors, including Nardil and Parnate
Sedatives such as Nembutal and Seconal
Tranquilizers such as Librium and Valium

Special precautions if you are pregnant or breastfeeding

Because of possible harm to the unborn baby, Periactin should not be used during pregnancy unless it is clearly needed. Periactin should not be taken by a woman who is breastfeeding. If you have just given birth, you will need to choose between breastfeeding and taking Periactin.

Recommended dosage of Periactin

ADULTS

The usual initial dose is 4 milligrams (1 tablet) 3 times daily. Dosage may range from 4 to 20 milligrams a day, but most people will take between 12 and 16 milligrams. Some may need as much as 32 milligrams a day. If you are over 65, the doctor will probably keep the dosage relatively low.

CHILDREN

Ages 2 to 6 Years

The usual dose is 2 milligrams (one-half tablet) 2 or 3 times a day; your doctor may adjust the dose if necessary. A child this age should not take more than 12 milligrams a day.

Ages 7 to 14 Years

The usual dose is 4 milligrams (1 tablet) 2 or 3 times a day; your doctor may adjust the dose if needed. A child this age should not take more than 16 milligrams a day.

Overdosage

Any drug taken in excess may have serious consequences. An overdose of Periactin can be fatal. If you suspect an overdose, seek medical attention urgently.

• Some symptoms of Periactin overdose are listed below:
  Dilated pupils, dry mouth, extreme excitement and agitation, fever, flushing, stomach or bowel distress, stupor or coma

Overdosage in children may produce hallucinations and convulsions.

Images